GABRG3

GABRG3
Identifiers
Aliases	GABRG3, gamma-aminobutyric acid type A receptor gamma3 subunit, gamma-aminobutyric acid type A receptor subunit gamma3
External IDs	OMIM: 600233; MGI: 95624; HomoloGene: 22444; GeneCards: GABRG3; OMA:GABRG3 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	27,541,984 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	57,036,936 bp
RNA expression pattern
	Top expressed in
	testicle; ; right testis; ; left testis; ; prefrontal cortex; ; gonad; ; anterior pituitary; ; sperm; ; Brodmann area 9; ; hypothalamus; ; cingulate gyrus;
	Top expressed in
	epithelium of lens; ; lumbar subsegment of spinal cord; ; nucleus accumbens; ; superior frontal gyrus; ; lateral septal nucleus; ; dorsal striatum; ; prefrontal cortex; ; dentate gyrus of hippocampal formation granule cell; ; lumbar spinal ganglion; ; primary visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chloride channel activity; extracellular ligand-gated ion channel activity; GABA-A receptor activity; ion channel activity; transmembrane signaling receptor activity; inhibitory extracellular ligand-gated ion channel activity; benzodiazepine receptor activity; GABA-gated chloride ion channel activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; cell junction; plasma membrane; postsynaptic membrane; synapse; membrane; chloride channel complex; GABA-ergic synapse; integral component of synaptic membrane; integral component of plasma membrane; dendrite membrane; neuron projection; postsynapse; GABA-A receptor complex;
Biological process	gamma-aminobutyric acid signaling pathway; chloride transport; chloride transmembrane transport; ion transport; ion transmembrane transport; signal transduction; chemical synaptic transmission; regulation of membrane potential; nervous system process; synaptic transmission, GABAergic; regulation of postsynaptic membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	2567
	14407
	ENSG00000182256
	ENSMUSG00000055026
	Q99928
	P27681
	NM_001270873; NM_033223
	NM_008074; NM_177273
	NP_001257802; NP_150092
	NP_032100
	Wikidata
View/Edit Human	View/Edit Mouse

GABA_A receptor-γ3, also known as GABRG3, is a protein which in humans is encoded by the GABRG3 gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182256 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000055026 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000182256 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000055026 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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