GAPDHS

GAPDHS
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3H9E, 3PFW, 5C7O, 5C7L
Identifiers
Aliases	GAPDHS, GAPD2, GAPDH-2, GAPDS, HSD-35, HEL-S-278, glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
External IDs	OMIM: 609169; MGI: 95653; HomoloGene: 101265; GeneCards: GAPDHS; OMA:GAPDHS - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	35,545,319 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	30,443,106 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; sperm; ; testicle; ; skin of leg; ; skin of abdomen; ; granulocyte; ; right uterine tube; ; tail of epididymis; ; metanephros;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; gastrula; ; embryo; ; tail of embryo; ; neural layer of retina; ; blastocyst; ; tibiofemoral joint; ; muscle of thigh;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; NAD binding; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; protein binding; NADP binding; glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;
Cellular component	cytoplasm; cytosol; nucleus;
Biological process	flagellated sperm motility; gluconeogenesis; glycolytic process; positive regulation of glycolytic process; canonical glycolysis; glucose metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	26330
	14447
	ENSG00000105679
	ENSMUSG00000061099
	O14556
	Q64467
	NM_014364
	NM_001290631; NM_008085
	NP_055179
	NP_001277560; NP_032111
	Wikidata
View/Edit Human	View/Edit Mouse

Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic or glyceraldehyde-3-phosphate dehydrogenase, testis-specific is an enzyme that in humans is encoded by the GAPDHS gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105679 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000061099 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Welch JE, Brown PL, O'Brien DA, Magyar PL, Bunch DO, Mori C, Eddy EM (Apr 2000). "Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells". Journal of Andrology. 21 (2): 328–38. doi:10.1002/j.1939-4640.2000.tb02111.x. PMID 10714828. S2CID 28139434.
^ "Entrez Gene: GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105679 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000061099 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10714828-5] Welch JE, Brown PL, O'Brien DA, Magyar PL, Bunch DO, Mori C, Eddy EM (Apr 2000). "Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells". Journal of Andrology. 21 (2): 328–38. doi:10.1002/j.1939-4640.2000.tb02111.x. PMID 10714828. S2CID 28139434.

[entrez-6] "Entrez Gene: GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic".

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