GLRA2

GLRA2
Identifiers
Aliases	GLRA2, GLR, glycine receptor alpha 2, MRXSP
External IDs	OMIM: 305990; MGI: 95748; HomoloGene: 31070; GeneCards: GLRA2; OMA:GLRA2 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	14,731,812 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	164,110,389 bp
RNA expression pattern
	Top expressed in
	testicle; ; ganglionic eminence; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; hypothalamus; ; prefrontal cortex; ; ventricular zone; ; rectum; ; cingulate gyrus; ; anterior cingulate cortex;
	Top expressed in
	lumbar subsegment of spinal cord; ; ventral tegmental area; ; lateral hypothalamus; ; lateral septal nucleus; ; anterior amygdaloid area; ; paraventricular nucleus of hypothalamus; ; nucleus of stria terminalis; ; nucleus accumbens; ; substantia nigra; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; glycine binding; transmitter-gated ion channel activity; chloride channel activity; glycine-gated chloride ion channel activity; extracellularly glycine-gated chloride channel activity; extracellular ligand-gated ion channel activity; ion channel activity; transmembrane signaling receptor activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	synapse; integral component of membrane; cell projection; cell junction; integral component of plasma membrane; postsynaptic membrane; membrane; chloride channel complex; plasma membrane; neuron projection; glycinergic synapse;
Biological process	neuropeptide signaling pathway; chloride transmembrane transport; chloride transport; ion transport; cellular response to amino acid stimulus; synaptic transmission, glycinergic; cellular response to ethanol; cellular response to zinc ion; excitatory postsynaptic potential; ion transmembrane transport; signal transduction; chemical synaptic transmission; regulation of membrane potential; response to amino acid; nervous system process; regulation of postsynaptic membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	2742
	237213
	ENSG00000101958
	ENSMUSG00000018589
	P23416
	Q7TNC8
	NM_001118885; NM_001118886; NM_001171942; NM_002063
	NM_183427; NM_001357099; NM_001357100
	NP_001112357; NP_001112358; NP_001165413; NP_002054
	NP_906272; NP_001344028; NP_001344029
	Wikidata
View/Edit Human	View/Edit Mouse

Glycine receptor subunit alpha-2 is a protein that in humans is encoded by the GLRA2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000101958 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018589 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GLRA2 glycine receptor, alpha 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000101958 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018589 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GLRA2 glycine receptor, alpha 2".

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