GLRB

GLRB
Identifiers
AliasesGLRB, HKPX2, glycine receptor beta
External IDsOMIM: 138492; MGI: 95751; HomoloGene: 20224; GeneCards: GLRB; OMA:GLRB - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000824
NM_001166060
NM_001166061

RefSeq (protein)

NP_000815
NP_001159532
NP_001159533

Location (UCSC)Chr 4: 157.08 – 157.17 MbChr 3: 80.75 – 80.82 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Glycine receptor subunit beta is a protein that in humans is encoded by the GLRB gene.[5][6][7]

The inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha (GLRA1, MIM 138491; GLRA2, MIM 305990) and beta subunits.[supplied by OMIM][7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000109738Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028020Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Milani N, Mulhardt C, Weber RG, Lichter P, Kioschis P, Poustka A, Becker CM (Oct 1998). "The human glycine receptor beta subunit gene (GLRB): structure, refined chromosomal localization, and population polymorphism". Genomics. 50 (3): 341–5. doi:10.1006/geno.1998.5324. PMID 9676428.
  6. ^ Handford CA, Lynch JW, Baker E, Webb GC, Ford JH, Sutherland GR, Schofield PR (Oct 1996). "The human glycine receptor beta subunit: primary structure, functional characterisation and chromosomal localisation of the human and murine genes". Brain Res Mol Brain Res. 35 (1–2): 211–9. doi:10.1016/0169-328x(95)00218-h. PMID 8717357.
  7. ^ a b "Entrez Gene: GLRB glycine receptor, beta".