GNPDA2

GNPDA2
Identifiers
Aliases	GNPDA2, GNP2, SB52, glucosamine-6-phosphate deaminase 2
External IDs	OMIM: 613222; MGI: 1915230; HomoloGene: 12381; GeneCards: GNPDA2; OMA:GNPDA2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	44,726,588 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	69,749,683 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Achilles tendon; ; ventricular zone; ; islet of Langerhans; ; ganglionic eminence; ; smooth muscle tissue; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; Brodmann area 9; ; Descending thoracic aorta;
	Top expressed in
	spermatid; ; olfactory epithelium; ; zygote; ; secondary oocyte; ; lumbar spinal ganglion; ; atrioventricular valve; ; primary oocyte; ; lateral septal nucleus; ; ventromedial nucleus; ; seminiferous tubule;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; hydrolase activity; glucosamine-6-phosphate deaminase activity; identical protein binding;
Cellular component	nucleus; cytosol; cytoplasm;
Biological process	N-acetylglucosamine metabolic process; glucosamine catabolic process; carbohydrate metabolic process; N-acetylglucosamine catabolic process; UDP-N-acetylglucosamine biosynthetic process; N-acetylneuraminate catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	132789
	67980
	ENSG00000163281
	ENSMUSG00000029209
	Q8TDQ7
	Q9CRC9
	NM_001270880; NM_001270881; NM_138335
	NM_001038015; NM_027681; NM_001347363; NM_001359239
	NP_001257809; NP_001257810; NP_612208
	NP_001033104; NP_001334292; NP_001346168
	Wikidata
View/Edit Human	View/Edit Mouse

Glucosamine-6-phosphate deaminase 2 also known as GNPDA2 is an enzyme that in humans is encoded by the GNPDA2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163281 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029209 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Arreola R, Valderrama B, Morante ML, Horjales E (September 2003). "Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study". FEBS Lett. 551 (1–3): 63–70. doi:10.1016/S0014-5793(03)00896-2. PMID 12965206. S2CID 45050024.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163281 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029209 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12965206-5] Arreola R, Valderrama B, Morante ML, Horjales E (September 2003). "Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study". FEBS Lett. 551 (1–3): 63–70. doi:10.1016/S0014-5793(03)00896-2. PMID 12965206. S2CID 45050024.

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