GPR101

GPR101
Identifiers
Aliases	GPR101, GPCR6, PAGH2, G protein-coupled receptor 101, PITA2
External IDs	OMIM: 300393; MGI: 2685211; HomoloGene: 14273; GeneCards: GPR101; OMA:GPR101 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	137,033,995 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	56,549,117 bp
RNA expression pattern
	Top expressed in
	nucleus accumbens; ; caudate nucleus; ; hypothalamus; ; putamen; ; cerebellum; ; cerebellar cortex; ; cerebellar hemisphere; ; spinal cord; ; temporal lobe; ; C1 segment;
	Top expressed in
	arcuate nucleus; ; lumbar subsegment of spinal cord; ; paraventricular nucleus of hypothalamus; ; subiculum; ; median eminence; ; dorsomedial hypothalamic nucleus; ; anterior amygdaloid area; ; ventromedial nucleus; ; nucleus accumbens; ; nucleus of stria terminalis;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; adrenergic receptor activity;
Cellular component	integral component of membrane; receptor complex; plasma membrane; integral component of plasma membrane; membrane; intracellular anatomical structure;
Biological process	adenylate cyclase-activating adrenergic receptor signaling pathway; cell-cell signaling; G protein-coupled receptor signaling pathway; signal transduction; adenylate cyclase-modulating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	83550
	245424
	ENSG00000165370
	ENSMUSG00000036357
	Q96P66
	Q80T62
	NM_054021
	NM_001033360
	NP_473362
	NP_001028532
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 101 is a protein that in humans is encoded by the GPR101 gene.^[5]^[6]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000165370 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000036357 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
^ ^a ^b "Entrez Gene: GPR101 G protein-coupled receptor 101".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000165370 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036357 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11574155-5] Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.

[entrez-6] "Entrez Gene: GPR101 G protein-coupled receptor 101".

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