GPR144

ADGRD2
Identifiers
Aliases	ADGRD2, PGR24, GPR144, adhesion G protein-coupled receptor D2
External IDs	HomoloGene: 130029; GeneCards: ADGRD2; OMA:ADGRD2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	124,478,589 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; triceps brachii muscle; ; vena cava; ; right ventricle; ; dorsal motor nucleus of vagus nerve; ; pituitary gland; ; anterior pituitary; ; lateral nuclear group of thalamus; ; inferior olivary nucleus; ; cerebellar vermis;
	n/a
	More reference expression data
	More reference expression data
Orthologs
	347088
	n/a
	ENSG00000180264
	n/a
	n; a
	n/a
	NM_001161808; NM_182611; NM_001395425
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

Probable G-protein coupled receptor 144 is a protein that in humans is encoded by the GPR144 gene.^[3]^[4] This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180264 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GPR144 G protein-coupled receptor 144".
^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. S2CID 7449692.
^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 978-1-4419-7912-4.
^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180264 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: GPR144 G protein-coupled receptor 144".

[pmid12435584-4] Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. S2CID 7449692.

[isbn1-4419-7912-3-5] Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 978-1-4419-7912-4.

[pmid22333914-6] Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914.

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