GPR149

GPR149
Identifiers
Aliases	GPR149, IEDA, PGR10, G protein-coupled receptor 149, R35
External IDs	MGI: 2443628; HomoloGene: 16359; GeneCards: GPR149; OMA:GPR149 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	154,430,190 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	62,512,561 bp
RNA expression pattern
	Top expressed in
	testicle; ; nucleus accumbens; ; caudate nucleus; ; putamen; ; pituitary gland; ; prefrontal cortex; ; superior frontal gyrus; ; anterior pituitary; ; hypothalamus; ; primary visual cortex;
	Top expressed in
	lumbar spinal ganglion; ; secondary oocyte; ; zygote; ; primary oocyte; ; ventromedial nucleus; ; olfactory tubercle; ; embryo; ; trigeminal ganglion; ; embryo; ; facial motor nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	neuropeptide binding; G protein-coupled receptor activity; signal transducer activity; melanin-concentrating hormone receptor activity; peptide binding;
Cellular component	integral component of membrane; neuron projection; plasma membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; negative regulation of ovulation; G protein-coupled receptor signaling pathway; neuropeptide signaling pathway; preantral ovarian follicle growth; antral ovarian follicle growth; signal transduction; chemical synaptic transmission;
	Sources:Amigo / QuickGO
Orthologs
	344758
	229357
	ENSG00000174948
	ENSMUSG00000043441
	Q86SP6
	Q3UVY1
	NM_001038705
	NM_177346; NM_001356525
	NP_001033794
	NP_796320; NP_001343454
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 149 is a protein that in humans is encoded by the GPR149 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000174948 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043441 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (Apr 2003). "The G protein-coupled receptor repertoires of human and mouse". Proc Natl Acad Sci U S A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
^ "Entrez Gene: GPR149 G protein-coupled receptor 149".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000174948 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000043441 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12679517-5] Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (Apr 2003). "The G protein-coupled receptor repertoires of human and mouse". Proc Natl Acad Sci U S A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.

[entrez-6] "Entrez Gene: GPR149 G protein-coupled receptor 149".

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