GPR174

GPR174
Identifiers
AliasesGPR174, GPCR17, LYPSR3, FKSG79, G protein-coupled receptor 174
External IDsOMIM: 300903; MGI: 2685222; HomoloGene: 13059; GeneCards: GPR174; OMA:GPR174 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032553

NM_001033251
NM_001177781
NM_001177782
NM_001358747

RefSeq (protein)

NP_115942

NP_001028423
NP_001171252
NP_001171253
NP_001345676

Location (UCSC)Chr X: 79.14 – 79.18 MbChr X: 106.3 – 106.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 174 is a protein that in humans is encoded by the GPR174 gene.[5] The receptor has been reported to bind to lysophosphatidylserine. [6] [7]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147138Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000073008Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: GPR174 G protein-coupled receptor 174".
  6. ^ Liu G, Li X, Wang Y, Zhang X, Gong W (2023). "Structural basis for ligand recognition and signaling of the lysophosphatidylserine receptors GPR34 and GPR174". PLOS Biol. 21 (12): e3002387. doi:10.1371/journal.pbio.3002387. PMC 10721165. PMID 38048360.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  7. ^ Nie Y, Qiu Z, Chen S, Chen Z, Song X, Ma Y; et al. (2023). "Specific binding of GPR174 by endogenous lysophosphatidylserine leads to high constitutive Gs signaling". Nat Commun. 14 (1): 5901. doi:10.1038/s41467-023-41654-3. PMC 10516915. PMID 37737235.{{cite journal}}: CS1 maint: multiple names: authors list (link)