GPR27

GPR27
Identifiers
Aliases	GPR27, SREB1, G protein-coupled receptor 27
External IDs	OMIM: 605187; MGI: 1202299; HomoloGene: 7344; GeneCards: GPR27; OMA:GPR27 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	71,756,496 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	99,672,027 bp
RNA expression pattern
	Top expressed in
	internal globus pallidus; ; endothelial cell; ; superior vestibular nucleus; ; Brodmann area 23; ; subthalamic nucleus; ; inferior ganglion of vagus nerve; ; nucleus accumbens; ; spinal cord; ; caudate nucleus; ; C1 segment;
	Top expressed in
	olfactory tubercle; ; nucleus accumbens; ; anterior amygdaloid area; ; fossa; ; substantia nigra; ; ventromedial nucleus; ; lateral septal nucleus; ; vas deferens; ; Region I of hippocampus proper; ; subiculum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane;
Biological process	positive regulation of insulin secretion involved in cellular response to glucose stimulus; positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway; signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2850
	14761
	ENSG00000170837
	ENSMUSG00000072875
	Q9NS67
	O54897
	NM_018971
	NM_008158
	NP_061844
	NP_032184
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 27 is a protein that in humans is encoded by the GPR27 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170837 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000072875 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.
^ "Entrez Gene: GPR27 G protein-coupled receptor 27".