GPR4

GPR4
Identifiers
Aliases	GPR4, G protein-coupled receptor 4, GPR6C.l
External IDs	OMIM: 600551; MGI: 2441992; HomoloGene: 3867; GeneCards: GPR4; OMA:GPR4 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	45,602,212 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	18,958,099 bp
RNA expression pattern
	Top expressed in
	upper lobe of left lung; ; right lung; ; apex of heart; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; left ventricle; ; pericardium; ; subcutaneous adipose tissue; ; epithelium of colon; ; tibial nerve;
	Top expressed in
	molar; ; otolith organ; ; utricle; ; habenula; ; myocardium of ventricle; ; medial dorsal nucleus; ; seminiferous tubule; ; muscle of thigh; ; medial head of gastrocnemius muscle; ; embryo;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	negative regulation of angiogenesis; angiogenesis involved in wound healing; G protein-coupled receptor signaling pathway; glomerular mesangial cell development; signal transduction; response to acidic pH; positive regulation of Rho protein signal transduction; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2828
	319197
	ENSG00000177464
	ENSMUSG00000044317
	P46093
	Q8BUD0
	NM_005282
	NM_175668
	NP_005273
	NP_783599
	Wikidata
View/Edit Human	View/Edit Mouse

G-protein coupled receptor 4 is a protein that in humans is encoded by the GPR4 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000177464 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044317 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mahadevan MS, Baird S, Bailly JE, Shutler GG, Sabourin LA, Tsilfidis C, Neville CE, Narang M, Korneluk RG (Apr 1996). "Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3". Genomics. 30 (1): 84–8. doi:10.1006/geno.1995.0013. PMID 8595909.
^ "Entrez Gene: GPR4 G protein-coupled receptor 4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000177464 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044317 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8595909-5] Mahadevan MS, Baird S, Bailly JE, Shutler GG, Sabourin LA, Tsilfidis C, Neville CE, Narang M, Korneluk RG (Apr 1996). "Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3". Genomics. 30 (1): 84–8. doi:10.1006/geno.1995.0013. PMID 8595909.

[entrez-6] "Entrez Gene: GPR4 G protein-coupled receptor 4".

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