GPR50

GPR50
Identifiers
Aliases	GPR50, H9, Mel1c, G protein-coupled receptor 50
External IDs	OMIM: 300207; MGI: 1333877; HomoloGene: 3113; GeneCards: GPR50; OMA:GPR50 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	151,181,465 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	70,712,863 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; smooth muscle tissue; ; placenta; ; hypothalamus; ; ganglionic eminence; ; lymph node; ; islet of Langerhans; ; mucosa of esophagus; ; right adrenal cortex; ; uterus;
	Top expressed in
	median eminence; ; arcuate nucleus; ; gastrula; ; intestinal villus; ; Ileal epithelium; ; perirhinal cortex; ; entorhinal cortex; ; choroid plexus of fourth ventricle; ; tracheobronchial tree; ; CA3 field;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	melatonin receptor activity; G protein-coupled receptor activity; protein binding; signal transducer activity; identical protein binding;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane; nucleoplasm; plasma membrane;
Biological process	cell-cell signaling; G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	9248
	14765
	ENSG00000102195
	ENSMUSG00000056380
	Q13585
	O88495
	NM_004224
	NM_010340; NM_001308501
	NP_004215
	NP_001295430; NP_034470
	Wikidata
View/Edit Human	View/Edit Mouse

G protein-coupled receptor 50 is a protein which in humans is encoded by the GPR50 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000102195 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056380 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GPR50 G protein-coupled receptor 50".
^ Reppert SM, Weaver DR, Ebisawa T, Mahle CD, Kolakowski LF (May 1996). "Cloning of a melatonin-related receptor from human pituitary". FEBS Letters. 386 (2–3): 219–24. doi:10.1016/0014-5793(96)00437-1. PMID 8647286.
^ Gubitz AK, Reppert SM (January 1999). "Assignment of the melatonin-related receptor to human chromosome X (GPR50) and mouse chromosome X (Gpr50)". Genomics. 55 (2): 248–51. doi:10.1006/geno.1998.5661. PMID 9933574.