GPR61

GPR61
Identifiers
Aliases	GPR61, BALGR, GPCR3, G protein-coupled receptor 61
External IDs	OMIM: 606916; MGI: 2441719; HomoloGene: 12910; GeneCards: GPR61; OMA:GPR61 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	109,548,406 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	108,062,198 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; right frontal lobe; ; Brodmann area 9; ; testicle; ; anterior pituitary; ; right hemisphere of cerebellum; ; cingulate gyrus; ; anterior cingulate cortex; ; hypothalamus; ; nucleus accumbens;
	Top expressed in
	medial dorsal nucleus; ; medial geniculate nucleus; ; ventromedial nucleus; ; piriform cortex; ; inferior colliculi; ; lateral geniculate nucleus; ; central gray substance of midbrain; ; anterior amygdaloid area; ; paraventricular nucleus of hypothalamus; ; medial vestibular nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding; arrestin family protein binding;
Cellular component	integral component of membrane; receptor complex; membrane; plasma membrane; endosome; endosome membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; positive regulation of cAMP-mediated signaling;
	Sources:Amigo / QuickGO
Orthologs
	83873
	229714
	ENSG00000156097
	ENSMUSG00000046793
	Q9BZJ8
	Q8C010
	NM_031936; NM_001393907
	NM_175470; NM_001305461
	NP_114142
	NP_001292390
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 61 is a protein that in humans is encoded by the GPR61 gene.^[5]^[6]^[7]

This gene belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. The protein encoded by this gene is most closely related to biogenic amine receptors.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000156097 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000046793 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
^ Cikos S, Gregor P, Koppel J (Nov 2001). "Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain". Biochim Biophys Acta. 1521 (1–3): 66–72. doi:10.1016/s0167-4781(01)00289-5. PMID 11690637.
^ ^a ^b "Entrez Gene: GPR61 G protein-coupled receptor 61".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000156097 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000046793 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11165367-5] Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.

[pmid11690637-6] Cikos S, Gregor P, Koppel J (Nov 2001). "Cloning of a novel biogenic amine receptor-like G protein-coupled receptor expressed in human brain". Biochim Biophys Acta. 1521 (1–3): 66–72. doi:10.1016/s0167-4781(01)00289-5. PMID 11690637.

[entrez-7] "Entrez Gene: GPR61 G protein-coupled receptor 61".

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