GPR62

GPR62
Identifiers
Aliases	GPR62, GPCR8, KPG_005, G protein-coupled receptor 62
External IDs	OMIM: 606917; MGI: 3525078; HomoloGene: 50962; GeneCards: GPR62; OMA:GPR62 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	51,957,499 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	106,343,137 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; C1 segment; ; internal globus pallidus; ; subthalamic nucleus; ; endothelial cell; ; ventral tegmental area; ; corpus callosum; ; substantia nigra; ; external globus pallidus; ; medulla oblongata;
	Top expressed in
	lumbar subsegment of spinal cord; ; seminiferous tubule; ; deep cerebellar nuclei; ; substantia nigra; ; anterior horn of spinal cord; ; suprachiasmatic nucleus; ; pontine nuclei; ; lateral geniculate nucleus; ; spermatocyte; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding; identical protein binding; arrestin family protein binding;
Cellular component	integral component of membrane; receptor complex; membrane; plasma membrane; endosome; endosome membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; positive regulation of cAMP-mediated signaling; inositol phosphate-mediated signaling;
	Sources:Amigo / QuickGO
Orthologs
	118442
	436090
	ENSG00000180929
	ENSMUSG00000091735
	Q9BZJ7
	Q80UC6
	NM_080865
	NM_001159652
	NP_543141
	NP_001153124
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.^[5]^[6]

G protein–coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180929 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000091735 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.
^ ^a ^b "Entrez Gene: GPR62 G protein-coupled receptor 62".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180929 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000091735 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11165367-5] Lee DK, George SR, Cheng R, Nguyen T, Liu Y, Brown M, Lynch KR, O'Dowd BF (Feb 2001). "Identification of four novel human G protein-coupled receptors expressed in the brain". Brain Res Mol Brain Res. 86 (1–2): 13–22. doi:10.1016/S0169-328X(00)00242-4. PMID 11165367.

[entrez-6] "Entrez Gene: GPR62 G protein-coupled receptor 62".

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