GPR68

GPR68
Identifiers
Aliases	GPR68, GPR12A, OGR1, G protein-coupled receptor 68, AI2A6
External IDs	OMIM: 601404; MGI: 2441763; HomoloGene: 2603; GeneCards: GPR68; OMA:GPR68 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	91,253,925 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	100,874,457 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; granulocyte; ; gingival epithelium; ; testicle; ; cardia; ; pylorus; ; buccal mucosa cell; ; saphenous vein; ; pituitary gland; ; human penis;
	Top expressed in
	zygote; ; oocyte; ; primary oocyte; ; secondary oocyte; ; mesenteric lymph nodes; ; lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; hippocampus proper; ; ciliary body;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; negative regulation of monocyte differentiation; positive regulation of insulin secretion involved in cellular response to glucose stimulus; cellular response to pH; inflammatory response; positive regulation of osteoclast development; signal transduction; positive regulation of insulin secretion;
	Sources:Amigo / QuickGO
Orthologs
	8111
	238377
	ENSG00000119714
	ENSMUSG00000047415
	Q15743
	Q8BFQ3
	NM_001177676; NM_003485; NM_001348437
	NM_001177673; NM_001177674; NM_175493
	NP_001171147; NP_003476; NP_001335366
	NP_001171144; NP_001171145; NP_780702; NP_001390243
	Wikidata
View/Edit Human	View/Edit Mouse

Ovarian cancer G-protein coupled receptor 1 is a protein that in humans is encoded by the GPR68 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119714 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047415 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Xu Y, Casey G (Sep 1996). "Identification of human OGR1, a novel G protein-coupled receptor that maps to chromosome 14". Genomics. 35 (2): 397–402. doi:10.1006/geno.1996.0377. PMID 8661159.
^ "Entrez Gene: GPR68 G protein-coupled receptor 68".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119714 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047415 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8661159-5] Xu Y, Casey G (Sep 1996). "Identification of human OGR1, a novel G protein-coupled receptor that maps to chromosome 14". Genomics. 35 (2): 397–402. doi:10.1006/geno.1996.0377. PMID 8661159.

[entrez-6] "Entrez Gene: GPR68 G protein-coupled receptor 68".

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