GPR85

GPR85
Identifiers
Aliases	GPR85, SREB, SREB2, G protein-coupled receptor 85
External IDs	OMIM: 605188; MGI: 1927851; HomoloGene: 10355; GeneCards: GPR85; OMA:GPR85 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	113,087,778 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	13,839,941 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; caudate nucleus; ; primary visual cortex; ; putamen; ; dorsolateral prefrontal cortex; ; ganglionic eminence; ; prefrontal cortex; ; lateral nuclear group of thalamus; ; nucleus accumbens; ; Brodmann area 23;
	Top expressed in
	barrel cortex; ; Rostral migratory stream; ; Region I of hippocampus proper; ; piriform cortex; ; ventromedial nucleus; ; substantia nigra; ; temporal lobe; ; facial motor nucleus; ; lobe of cerebellum; ; habenula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; protein binding; signal transducer activity;
Cellular component	integral component of membrane; endoplasmic reticulum; membrane; plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	54329
	64450
	ENSG00000164604
	ENSMUSG00000048216
	P60893
	P60894
	NM_001146265; NM_001146266; NM_001146267; NM_018970
	NM_145066; NM_001330666; NM_001330667
	NP_001139737; NP_001139738; NP_001139739; NP_061843
	NP_001317595; NP_001317596; NP_659503
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 85 is a protein that in humans is encoded by the GPR85 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164604 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048216 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hellebrand S, Schaller HC, Wittenberger T (September 2000). "The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31". Biochimica et Biophysica Acta. 1493 (1–2): 269–272. doi:10.1016/s0167-4781(00)00182-2. PMID 10978537.
^ Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, et al. (June 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochemical and Biophysical Research Communications. 272 (2): 576–582. doi:10.1006/bbrc.2000.2829. PMID 10833454.
^ "Entrez Gene: GPR85 G protein-coupled receptor 85".