GTF2F2

GTF2F2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1BBY, 1F3U, 2BBY, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Identifiers
Aliases	GTF2F2, BTF4, RAP30, TF2F2, TFIIF, general transcription factor IIF subunit 2
External IDs	OMIM: 189969; MGI: 1915955; HomoloGene: 37884; GeneCards: GTF2F2; OMA:GTF2F2 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	45,284,893 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	76,248,305 bp
RNA expression pattern
	Top expressed in
	gonad; ; ventricular zone; ; ganglionic eminence; ; Achilles tendon; ; muscle of thigh; ; skin of abdomen; ; testicle; ; skin of leg; ; Skeletal muscle tissue of biceps brachii; ; gastrocnemius muscle;
	Top expressed in
	embryo; ; morula; ; morula; ; epiblast; ; embryo; ; uterus; ; lens; ; zygote; ; spermatid; ; cervix;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; nucleotide binding; helicase activity; protein binding; hydrolase activity; ATP binding;
Cellular component	microtubule cytoskeleton; nucleoplasm; transcription factor TFIIF complex; nucleus; transcription preinitiation complex;
Biological process	mRNA splicing, via spliceosome; regulation of transcription, DNA-templated; transcription elongation from RNA polymerase II promoter; 7-methylguanosine mRNA capping; transcription by RNA polymerase II; positive regulation of transcription initiation from RNA polymerase II promoter; transcription, DNA-templated; positive regulation of viral transcription; transcription initiation from RNA polymerase II promoter; snRNA transcription by RNA polymerase II; fibroblast growth factor receptor signaling pathway; positive regulation of transcription elongation from RNA polymerase II promoter; RNA metabolic process; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	2963
	68705
	ENSG00000188342
	ENSMUSG00000067995
	P13984
	Q8R0A0
	NM_004128
	NM_026816
	NP_004119
	NP_081092
	Wikidata
View/Edit Human	View/Edit Mouse

General transcription factor IIF subunit 2 is a protein that in humans is encoded by the GTF2F2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188342 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000067995 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Heng HH, Xiao H, Shi XM, Greenblatt J, Tsui LC (May 1994). "Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome". Hum. Mol. Genet. 3 (1): 61–4. doi:10.1093/hmg/3.1.61. PMID 8162052.
^ "Entrez Gene: GTF2F2 general transcription factor IIF, polypeptide 2, 38kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000188342 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000067995 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8162052-5] Heng HH, Xiao H, Shi XM, Greenblatt J, Tsui LC (May 1994). "Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome". Hum. Mol. Genet. 3 (1): 61–4. doi:10.1093/hmg/3.1.61. PMID 8162052.

[entrez-6] "Entrez Gene: GTF2F2 general transcription factor IIF, polypeptide 2, 38kDa".

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