George IV Gurieli (Georgian: გიორგი IV გურიელი) (died 1726), of the House of Gurieli, was Prince of Guria from 1711 to 1726, and a king of Imereti in western Georgia in 1716. He was installed as regent of Guria by his father, Mamia III Gurieli, then the king of Imereti, in 1712. In 1716, he seized the crown of Imereti, but was forced to abandon the enterprise later that year. Returning to Guria, his rule was challenged by a faction of local nobility, which included his mother Elene and brother Kaikhosro III Gurieli. He was finally able to crush the opposition after making peace with Bezhan Dadiani, Prince of Mingrelia.