George Klein

George Klein may refer to:

• George Klein (inventor) (1904–1992), Canadian inventor
• George Klein (comics) (c. 1915 or 1920 – 1969), American comic book artist
• George Klein (biologist) (1925–2016), Hungarian-Swedish biologist and writer
• George Klein (physician), Canadian cardiologist
• George Klein (DJ) (1935–2019), disc jockey and television host
• George Klein (Canadian football) (1932–?), Canadian football player
• George S. Klein (1917–1971), American psychologist and psychoanalyst
• Adam Klein (swimmer) (George Klein IV, born 1988), American swimmer