George Worthington may refer to:
- George Worthington (businessman) (1813–1871), American merchant and banker
- George Worthington (tennis) (1928–1964), Australian tennis player
- George Worthington (bishop) (1840–1908), bishop of Nebraska
- George Worthington (cricketer) (1822–1900), English cricketer
This disambiguation page lists articles about people with the same name.
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