Germ cell tumor

Germ-cell tumor
Micrograph of a seminoma, a common germ cell tumor.
SpecialtyOncology

Germ cell tumor (GCT) is a neoplasm derived from the primordial germ cells.[1] Germ-cell tumors can be cancerous or benign. Germ cells normally occur inside the gonads (ovary[2] and testis). GCTs that originate outside the gonads may be birth defects resulting from errors during development of the embryo.

  1. ^ Harrison's principles of internal medicine (21st ed.). New York: McGraw Hill. 2022. p. 690. ISBN 978-1-264-26850-4.
  2. ^ Maoz A, Matsuo K, Ciccone MA, Matsuzaki S, Klar M, Roman LD, et al. (May 2020). "Molecular Pathways and Targeted Therapies for Malignant Ovarian Germ Cell Tumors and Sex Cord-Stromal Tumors: A Contemporary Review". Cancers. 12 (6): 1398. doi:10.3390/cancers12061398. PMC 7353025. PMID 32485873.