Globotriaosylceramide is a globoside.[1] It is also known as CD77, Gb3, GL3, and ceramide trihexoside.[2] It is one of the few clusters of differentiation that is not a protein.
It is formed by the alpha linkage of galactose to lactosylceramide catalyzed by A4GALT.
It is metabolized by alpha-galactosidase, which hydrolyzes the terminal alpha linkage.
- ^ globotriaosylceramide at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- ^ Bekri S, Lidove O, Jaussaud R, Knebelmann B, Barbey F (October 2006). "The role of ceramide trihexoside (globotriaosylceramide) in the diagnosis and follow-up of the efficacy of treatment of Fabry disease: a review of the literature". Cardiovasc Hematol Agents Med Chem. 4 (4): 289–97. doi:10.2174/187152506778520718. PMID 17073606. Archived from the original on 2013-04-14.
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