The Great Alliance for Change (Spanish: Gran Alianza por el cambio) was a political alliance between parties in Colombia during the 1998 Colombian presidential election that supported the presidency of Andres Pastrana Arango against the campaign of Colombian Liberal Party presidential candidacy of Horacio Serpa, back then supported by the presidency of Ernesto Samper.
The alliance formed as a response to the unpopularity of President Samper caused by the "8000 process scandal in which money from the Cali drug cartel entered the presidential campaign of Samper and in which Serpa was also involved as head of the campaign. The alliance united the official candidate for the Conservative party, Andres Pastrana and a fraction of the Colombian Liberal party led by Alfonso Valdivieso Sarmiento who had failed to win the party's nomination against Serpa. At last, they ended the Liberal Party 12-years ruled in Colombia.