  Street cartouche dated 1721 and the former home of Dorothy L. Sayers at No. 24 | |
 Vicinity of Great James Street (centre, vertical) | |
| Area | Bloomsbury, London |
|---|---|
| Postal code | WC1 |
| Coordinates | 51°31′18″N 0°07′02″W / 51.52179°N 0.11717°W |
| Construction | |
| Completion | c.1721 |
| Other | |
| Known for | Literary connections |
Great James Street is a street in the Bloomsbury district of the London Borough of Camden. It has strong literary and publishing connections, and former residents include the poet Algernon Charles Swinburne and the detective story writer Dorothy L. Sayers. The Nation & Athenaeum, chaired by John Maynard Keynes, and the Nonesuch Press were both based in the street. The street has almost all its original buildings with minimal external changes. It is described in Nikolaus Pevsner's guide as "a gem" and its mostly terraced houses as "unusually uniform for their date".[1] The majority of the street is listed by Historic England.