Great Meadows may refer to:
- Great Meadows, New Jersey, an unincorporated area within Liberty Township, New Jersey
- Battle of the Great Meadows or Battle of Fort Necessity, a 1754 battle of the French and Indian War in Pennsylvania
- Great Meadows National Wildlife Refuge, a wildlife refuge in Concord, Massachusetts
- Great Meadows (Connecticut River), a floodplain south of Hartford, Connecticut
- Great Meadows Salt Marsh, a unit of the Stewart B. McKinney National Wildlife Refuge in Connecticut
- Great Meadow, Ukraine (Ukrainian: Великий Луг, Velykyi Luh), a specific territory of the southern portions of Central Ukraine in several historical sources that was mostly flooded by the Kakhovka Reservoir until the destruction of the Kakhovka Dam