A guess is a conjecture or estimation. To "guess" is to make a prediction without sufficient information or knowledge.
Guess, GUESS, Guessing, or Guessie may also refer to:
- Guess (clothing), an American name-brand clothing line
- Guess, a 2024 song by Charli XCX
- Guess (variety show), a variety show in Taiwan
- Guess (JoJo's Bizarre Adventure), a character in the Japanese manga JoJo's Bizarre Adventure