| Guy Self | |
|---|---|
| Holby City character | |
 John Michie as Guy Self | |
| First appearance | "Sink or Swim" 26 November 2013 |
| Last appearance | Episode 1099 8 March 2022 |
| Created by | Oliver Kent |
| Portrayed by | John Michie |
| Spinoff(s) | Casualty (2014, 2016) |
| In-universe information | |
| Occupation | Consultant neurosurgeon (prev. Chief executive officer) |
| Family | Valerie Sturgeon (mother) |
| Spouse | Anya Self (deceased) |
| Children | Zosia March |
| Relatives | Arthur Valentine-Self (grandson) |
Guy Self is a fictional character from the BBC medical drama Holby City played by John Michie. He first appeared in the sixteenth series episode "Sink or Swim", broadcast on 26 November 2013. Guy is a consultant neurosurgeon and Holby City Hospital's chief executive officer (CEO) until he resigns from his CEO position. The character also appeared in Holby City's sister show, Casualty. Guy departed in the nineteenth series episode "Song of Self – Part Two", but returned for a nine episode guest stint later in the series. Michie has since reprised the role on three occasions: for one episode in 2018, ten episodes in 2020, and one episode in 2022.