HAS1

HAS1
Identifiers
Aliases	HAS1, HAS, hyaluronan synthase 1
External IDs	OMIM: 601463; MGI: 106590; HomoloGene: 1165; GeneCards: HAS1; OMA:HAS1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	51,723,991 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	18,075,467 bp
RNA expression pattern
	Top expressed in
	testicle; ; parietal pleura; ; vena cava; ; germinal epithelium; ; right ovary; ; synovial joint; ; left ovary; ; synovial membrane; ; pericardium; ; middle temporal gyrus;
	Top expressed in
	ankle joint; ; ankle; ; genital tubercle; ; tail of embryo; ; embryo; ; facial motor nucleus; ; trachea; ; aortic valve; ; submandibular gland; ; ascending aorta;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glycosyltransferase activity; transferase activity; hyaluronan synthase activity; protein binding; identical protein binding;
Cellular component	cytoplasm; integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	cell adhesion; negative regulation of fibroblast migration; hyaluronan biosynthetic process; cellular response to platelet-derived growth factor stimulus; extracellular matrix assembly; glycosaminoglycan biosynthetic process; extracellular polysaccharide biosynthetic process; estrous cycle;
	Sources:Amigo / QuickGO
Orthologs
	3036
	15116
	ENSG00000105509
	ENSMUSG00000003665
	Q92839
	Q61647
	NM_001297436; NM_001523
	NM_008215
	NP_001284365; NP_001514
	NP_032241
	Wikidata
View/Edit Human	View/Edit Mouse

Hyaluronan synthase 1 is an enzyme that in humans is encoded by the HAS1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105509 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003665 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Spicer AP, Seldin MF, Olsen AS, Brown N, Wells DE, Doggett NA, Itano N, Kimata K, Inazawa J, McDonald JA (Jul 1997). "Chromosomal localization of the human and mouse hyaluronan synthase genes". Genomics. 41 (3): 493–7. doi:10.1006/geno.1997.4696. PMID 9169154.
^ "Entrez Gene: HAS1 hyaluronan synthase 1".