HMGB3

HMGB3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EQZ, 2YQI
Identifiers
Aliases	HMGB3, HMG-2a, HMG-4, HMG2A, HMG4, high mobility group box 3
External IDs	OMIM: 300193; MGI: 1098219; HomoloGene: 84734; GeneCards: HMGB3; OMA:HMGB3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	150,990,771 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	70,604,282 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; ganglionic eminence; ; ventricular zone; ; buccal mucosa cell; ; placenta; ; islet of Langerhans; ; olfactory zone of nasal mucosa; ; right lobe of liver; ; mucosa of transverse colon; ; sural nerve;
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; tail of embryo; ; neural tube; ; mesencephalon; ; genital tubercle; ; lens; ; adrenal gland; ; yolk sac; ; bone marrow;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; double-stranded DNA binding; DNA binding, bending; protein binding; four-way junction DNA binding; RNA binding; transcription factor binding;
Cellular component	cytoplasm; nucleus; chromosome;
Biological process	multicellular organism development; immune system process; DNA recombination; innate immune response; regulation of transcription, DNA-templated; transcription, DNA-templated; DNA geometric change; negative regulation of B cell differentiation; negative regulation of myeloid cell differentiation; chromatin remodeling; regulation of transcription by RNA polymerase II; positive regulation of innate immune response; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3149
	15354
	ENSG00000029993
	ENSMUSG00000015217
	O15347
	O54879
	NM_005342; NM_001301228; NM_001301229; NM_001301231
	NM_001293623; NM_001293624; NM_001293625; NM_008253
	NP_001288157; NP_001288158; NP_001288160; NP_005333
	NP_001280552; NP_001280553; NP_001280554; NP_032279
	Wikidata
View/Edit Human	View/Edit Mouse

High-mobility group protein B3 is a protein that in humans is encoded by the HMGB3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000029993 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015217 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Vaccari T, Beltrame M, Ferrari S, Bianchi ME (April 1998). "Hmg4, a new member of the Hmg1/2 gene family". Genomics. 49 (2): 247–52. doi:10.1006/geno.1998.5214. PMID 9598312.
^ "Entrez Gene: HMGB3 high-mobility group box 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000029993 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000015217 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9598312-5] Vaccari T, Beltrame M, Ferrari S, Bianchi ME (April 1998). "Hmg4, a new member of the Hmg1/2 gene family". Genomics. 49 (2): 247–52. doi:10.1006/geno.1998.5214. PMID 9598312.

[entrez-6] "Entrez Gene: HMGB3 high-mobility group box 3".

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