HMGN1

HMGN1
Identifiers
Aliases	HMGN1, HMG14, high mobility group nucleosome binding domain 1
External IDs	OMIM: 163920; MGI: 96120; HomoloGene: 3643; GeneCards: HMGN1; OMA:HMGN1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	39,349,647 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	95,928,929 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; endometrium; ; right uterine tube; ; appendix; ; lymph node; ; olfactory zone of nasal mucosa; ; rectum; ; islet of Langerhans; ; bone marrow;
	Top expressed in
	neural layer of retina; ; yolk sac; ; ventricular zone; ; embryo; ; embryo; ; genital tubercle; ; tail of embryo; ; lip; ; zygote; ; right kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleosomal DNA binding; DNA binding; chromatin binding;
Cellular component	cytoplasm; chromatin; nucleus; nucleoplasm;
Biological process	positive regulation of DNA-templated transcription, elongation; pyrimidine dimer repair by nucleotide-excision repair; transcription-coupled nucleotide-excision repair; chromatin organization; regulation of transcription by RNA polymerase II; response to UV-B; response to UV-C; regulation of development, heterochronic; post-embryonic camera-type eye morphogenesis; regulation of epithelial cell proliferation; positive regulation of NAD+ ADP-ribosyltransferase activity;
	Sources:Amigo / QuickGO
Orthologs
	3150
	15312
	ENSG00000205581
	ENSMUSG00000040681
	P05114
	P18608
	NM_004965
	NM_008251
	NP_004956
	NP_032277
	Wikidata
View/Edit Human	View/Edit Mouse

Non-histone chromosomal protein HMG-14 is a protein that in humans is encoded by the HMGN1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000205581 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040681 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Landsman D, Srikantha T, Westermann R, Bustin M (Dec 1986). "Chromosomal protein HMG-14. Complete human cDNA sequence and evidence for a multigene family". The Journal of Biological Chemistry. 261 (34): 16082–6. doi:10.1016/S0021-9258(18)66680-3. PMID 3782107.
^ Landsman D, McBride OW, Soares N, Crippa MP, Srikantha T, Bustin M (Feb 1989). "Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family". The Journal of Biological Chemistry. 264 (6): 3421–7. doi:10.1016/S0021-9258(18)94084-6. PMID 2563381.
^ "Entrez Gene: HMGN1 high-mobility group nucleosome binding domain 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000205581 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040681 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid3782107-5] Landsman D, Srikantha T, Westermann R, Bustin M (Dec 1986). "Chromosomal protein HMG-14. Complete human cDNA sequence and evidence for a multigene family". The Journal of Biological Chemistry. 261 (34): 16082–6. doi:10.1016/S0021-9258(18)66680-3. PMID 3782107.

[pmid2563381-6] Landsman D, McBride OW, Soares N, Crippa MP, Srikantha T, Bustin M (Feb 1989). "Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family". The Journal of Biological Chemistry. 264 (6): 3421–7. doi:10.1016/S0021-9258(18)94084-6. PMID 2563381.

[entrez-7] "Entrez Gene: HMGN1 high-mobility group nucleosome binding domain 1".

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