HMHA1

ARHGAP45
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3D25, 3FT3
Identifiers
Aliases	ARHGAP45, HA-1, HLA-HA1, HMHA1, histocompatibility (minor) HA-1, Rho GTPase activating protein 45
External IDs	OMIM: 601155; MGI: 1917969; HomoloGene: 69120; GeneCards: ARHGAP45; OMA:ARHGAP45 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	1,086,628 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	79,867,306 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; spleen; ; oocyte; ; secondary oocyte; ; monocyte; ; lymph node; ; thymus; ; appendix; ; bone marrow cells;
	Top expressed in
	granulocyte; ; thymus; ; mesenteric lymph nodes; ; blood; ; spleen; ; tibiofemoral joint; ; bone marrow; ; stroma of bone marrow; ; subcutaneous adipose tissue; ; ankle joint;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; GTPase activator activity;
Cellular component	cytosol; extracellular region; secretory granule lumen; azurophil granule lumen; cytoplasm; plasma membrane; membrane; ruffle membrane; cell projection;
Biological process	positive regulation of GTPase activity; intracellular signal transduction; regulation of small GTPase mediated signal transduction; signal transduction; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	23526
	70719
	ENSG00000180448
	ENSMUSG00000035697
	Q92619
	Q3TBD2
	NM_001258328; NM_001282334; NM_001282335; NM_012292; NM_001321232
	NM_001142701; NM_027521; NM_001347074
	NP_001245257; NP_001269263; NP_001269264; NP_001308161; NP_036424
	NP_001136173; NP_001334003; NP_081797
	Wikidata
View/Edit Human	View/Edit Mouse

Minor histocompatibility protein HA-1 is a protein that in humans is encoded by the HMHA1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000180448 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035697 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wilke M, Pool J, den Haan JM, Goulmy E (Jan 1999). "Genomic identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR". Tissue Antigens. 52 (4): 312–317. doi:10.1111/j.1399-0039.1998.tb03053.x. PMID 9820596.
^ Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (May 1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–329. doi:10.1093/dnares/3.5.321. PMID 9039502.
^ "Entrez Gene: HMHA1 histocompatibility (minor) HA-1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000180448 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035697 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9820596-5] Wilke M, Pool J, den Haan JM, Goulmy E (Jan 1999). "Genomic identification of the minor histocompatibility antigen HA-1 locus by allele-specific PCR". Tissue Antigens. 52 (4): 312–317. doi:10.1111/j.1399-0039.1998.tb03053.x. PMID 9820596.

[pmid9039502-6] Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (May 1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–329. doi:10.1093/dnares/3.5.321. PMID 9039502.

[entrez-7] "Entrez Gene: HMHA1 histocompatibility (minor) HA-1".

[1]

[2]

[3]

[4]

[5]

[6]

[7]