HOXA11

HOXA11
Identifiers
Aliases	HOXA11, HOX1, HOX1I, RUSAT1, homeobox A11
External IDs	OMIM: 142958; MGI: 96172; HomoloGene: 4033; GeneCards: HOXA11; OMA:HOXA11 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	27,185,232 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	52,222,790 bp
RNA expression pattern
	Top expressed in
	body of uterus; ; myometrium; ; canal of the cervix; ; stromal cell of endometrium; ; ectocervix; ; muscle layer of sigmoid colon; ; tibial arteries; ; transverse colon; ; prostate; ; urinary bladder;
	Top expressed in
	gastrula; ; decidua; ; tail of embryo; ; uterus; ; vas deferens; ; elbow; ; lumbar subsegment of spinal cord; ; blastocyst; ; transitional epithelium of urinary bladder; ; ankle joint;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	transcription regulator complex; protein-DNA complex; nucleus; nucleoplasm; protein-containing complex;
Biological process	cartilage development involved in endochondral bone morphogenesis; skeletal system development; proximal/distal pattern formation; regulation of chondrocyte differentiation; male gonad development; regulation of transcription, DNA-templated; organ induction; anatomical structure morphogenesis; embryonic digit morphogenesis; transcription, DNA-templated; single fertilization; uterus development; multicellular organism development; positive regulation of transcription, DNA-templated; branching involved in ureteric bud morphogenesis; developmental growth; embryonic limb morphogenesis; positive regulation of chondrocyte differentiation; spermatogenesis; positive regulation of cell development; regulation of gene expression; embryonic skeletal joint morphogenesis; metanephros development; mesodermal cell fate specification; dorsal/ventral pattern formation; embryonic forelimb morphogenesis; anterior/posterior pattern specification; bone development; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3207
	15396
	ENSG00000005073
	ENSMUSG00000038210
	P31270
	P31311
	NM_005523
	NM_010450
	NP_005514
	NP_034580
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000005073 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038210 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.
^ "Entrez Gene: HOXA11 homeobox A11".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000005073 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038210 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

[entrez-7] "Entrez Gene: HOXA11 homeobox A11".

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