HOXA5

HOXA5
Identifiers
Aliases	HOXA5, HOX1, HOX1.3, HOX1C, homeobox A5
External IDs	OMIM: 142952; MGI: 96177; HomoloGene: 40726; GeneCards: HOXA5; OMA:HOXA5 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	27,143,681 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	52,181,567 bp
RNA expression pattern
	Top expressed in
	caput epididymis; ; corpus epididymis; ; renal medulla; ; left uterine tube; ; adrenal cortex; ; right adrenal cortex; ; left adrenal cortex; ; mucosa of transverse colon; ; mucosa of ileum; ; right uterine tube;
	Top expressed in
	axial skeleton; ; human vertebral column; ; cervical vertebral column; ; thoracic vertebral column; ; efferent ductule; ; left lung lobe; ; migratory enteric neural crest cell; ; rib; ; right lung lobe; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding;
Cellular component	nucleus;
Biological process	embryonic skeletal system morphogenesis; pattern specification process; skeletal system development; respiratory system process; regulation of transcription, DNA-templated; multicellular organism growth; lung development; trachea morphogenesis; bronchiole development; cell-cell signaling involved in mammary gland development; regulation of mammary gland epithelial cell proliferation; mammary gland alveolus development; lung goblet cell differentiation; transcription, DNA-templated; mammary gland epithelial cell differentiation; negative regulation of erythrocyte differentiation; respiratory gaseous exchange by respiratory system; trachea cartilage morphogenesis; embryonic skeletal system development; morphogenesis of an epithelium; multicellular organism development; thyroid gland development; lobar bronchus epithelium development; mesenchymal-epithelial cell signaling; positive regulation of apoptotic process; intestinal epithelial cell maturation; negative regulation of angiogenesis; cartilage morphogenesis; lung alveolus development; lung-associated mesenchyme development; epithelial tube branching involved in lung morphogenesis; cell migration; positive regulation of myeloid cell differentiation; anterior/posterior pattern specification; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3202
	15402
	ENSG00000106004
	ENSMUSG00000038253
	P20719
	P09021
	NM_019102
	NM_010453
	NP_061975
	NP_034583
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-A5 is a protein that in humans is encoded by the HOXA5 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106004 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038253 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.
^ "Entrez Gene: HOXA5 homeobox A5".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000106004 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038253 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

[entrez-7] "Entrez Gene: HOXA5 homeobox A5".

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