HOXB1

HOXB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1B72
Identifiers
Aliases	HOXB1, HCFP3, HOX2, HOX2I, Hox-2.9, homeobox B1
External IDs	OMIM: 142968; MGI: 96182; HomoloGene: 1615; GeneCards: HOXB1; OMA:HOXB1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	48,531,011 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	96,259,082 bp
RNA expression pattern
	Top expressed in
	kidney; ; gonad; ; human kidney; ; renal cortex; ; cervix; ; uterine tube; ; urinary bladder; ; right uterine tube; ; olfactory zone of nasal mucosa; ; zone of skin;
	Top expressed in
	primitive streak; ; tail of embryo; ; embryo; ; Ileal epithelium; ; embryonic organizer; ; embryo; ; somite; ; neuromere; ; rhombomere; ; pharynx;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; protein domain specific binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	multicellular organism development; pattern specification process; regulation of transcription, DNA-templated; transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; anatomical structure morphogenesis; anterior/posterior pattern specification; rhombomere development; rhombomere 4 development; rhombomere 5 development; facial nerve structural organization; facial nucleus development; anatomical structure formation involved in morphogenesis; embryonic skeletal system morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	3211
	15407
	ENSG00000120094
	ENSMUSG00000018973
	P14653
	P17919
	NM_002144
	NM_008266
	NP_002135
	NP_032292
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120094 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018973 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (August 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (December 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.
^ "Entrez Gene: HOXB1 homeobox B1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000120094 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018973 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (August 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (December 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

[entrez-7] "Entrez Gene: HOXB1 homeobox B1".

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