HOXC6

HOXC6
Identifiers
AliasesHOXC6, CP25, HHO.C8, HOX3, HOX3C, homeobox C6
External IDsOMIM: 142972; MGI: 96197; HomoloGene: 19533; GeneCards: HOXC6; OMA:HOXC6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_153693
NM_004503

NM_010465

RefSeq (protein)

NP_004494
NP_710160

NP_034595

Location (UCSC)Chr 12: 53.99 – 54.03 MbChr 15: 102.91 – 102.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox protein Hox-C6 is a protein that in humans is encoded by the HOXC6 gene.[5][6][7] Hox-C6 expression is highest in the fallopian tube and ovary.[8] HoxC6 has been highly expressed in many types of cancers including prostate, breast, and esophageal squamous cell cancer.[9]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197757Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000001661Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
  6. ^ Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–553. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.
  7. ^ "Entrez Gene: HOXC6 homeobox C6".
  8. ^ "Tissue expression of HOXC6 - Summary - The Human Protein Atlas". www.proteinatlas.org. Retrieved 2022-04-11.
  9. ^ Tang L, Cao Y, Song X, Wang X, Li Y, Yu M, et al. (2019-03-14). "HOXC6 promotes migration, invasion and proliferation of esophageal squamous cell carcinoma cells via modulating expression of genes involved in malignant phenotypes". PeerJ. 7: e6607. doi:10.7717/peerj.6607. PMC 6421064. PMID 30886783.