HOXD4

HOXD4
Identifiers
Aliases	HOXD4, HHO.C13, HOX-5.1, HOX4, HOX4B, Hox-4.2, homeobox D4
External IDs	OMIM: 142981; MGI: 96208; HomoloGene: 7773; GeneCards: HOXD4; OMA:HOXD4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	176,153,226 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	74,559,504 bp
RNA expression pattern
	Top expressed in
	body of uterus; ; right uterine tube; ; corpus epididymis; ; testicle; ; right ovary; ; left ovary; ; left uterine tube; ; tail of epididymis; ; human kidney; ; left adrenal cortex;
	Top expressed in
	cervical vertebral column; ; thoracic vertebral column; ; tail of embryo; ; lumbar subsegment of spinal cord; ; enteric nervous system; ; lactiferous gland; ; genital tubercle; ; embryo; ; transitional epithelium of urinary bladder; ; uterus;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; sequence-specific DNA binding; DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cell junction;
Biological process	transcription, DNA-templated; regulation of transcription, DNA-templated; multicellular organism development; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; skeletal system development; anterior/posterior pattern specification; embryonic skeletal system morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	3233
	15436
	ENSG00000170166
	ENSMUSG00000101174
	P09016
	P10628
	NM_014621
	NM_010469
	NP_055436
	NP_034599
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-D4 is a protein that in humans is encoded by the HOXD4 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170166 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000101174 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.
^ "Entrez Gene: HOXD4 homeobox D4".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000170166 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000101174 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

[entrez-7] "Entrez Gene: HOXD4 homeobox D4".

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