Protein-coding gene in the species Homo sapiens
17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene .[ 5] [ 6]
17β-HSD13 is significantly up-regulated in the liver of patients with non-alcoholic fatty liver disease (NAFLD) and enhances lipogenesis .[ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000170509 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034528 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Zhu YS, Imperato-McGinley JL (9 November 2016). "4.02: Disorders of Sexual Development in Males: Molecular Genetics, Epigenetics, Gender Identity, and Cognition" . In Lightman S (ed.). Hormones, Brain and Behavior . Vol. 4: Clinical Important Effects of Hormones on Brain and Behavior. Elsevier Science. p. 69. ISBN 978-0-12-803608-2 .
^ Zanders ED (9 November 2015). "Enzymes, Part 2" . Human Drug Targets: A Compendium for Pharmaceutical Discovery . John Wiley & Sons. pp. 257–. ISBN 978-1-118-84985-9 .
^ Su W, Wang Y, Jia X, Wu W, Li L, Tian X, et al. (August 2014). "Comparative proteomic study reveals 17β-HSD13 as a pathogenic protein in nonalcoholic fatty liver disease" . Proceedings of the National Academy of Sciences of the United States of America . 111 (31): 11437–11442. Bibcode :2014PNAS..11111437S . doi :10.1073/pnas.1410741111 . PMC 4128098 . PMID 25028495 .