HTR3C

HTR3C
Identifiers
Aliases	HTR3C, 5-hydroxytryptamine receptor 3C
External IDs	OMIM: 610121; HomoloGene: 50847; GeneCards: HTR3C; OMA:HTR3C - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	184,060,673 bp
RNA expression pattern
	Top expressed in
	testicle; ; right lung; ; mucosa of transverse colon; ; upper lobe of left lung; ; duodenum; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; gallbladder; ; myometrium; ; skin of abdomen;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; extracellular ligand-gated ion channel activity; serotonin-gated cation-selective channel activity; ion channel activity; transmembrane signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane; neuron projection; synapse;
Biological process	ion transport; signal transduction; ion transmembrane transport; serotonin receptor signaling pathway; chemical synaptic transmission; regulation of membrane potential; nervous system process;
	Sources:Amigo / QuickGO
Orthologs
	170572
	n/a
	ENSG00000178084
	n/a
	Q8WXA8
	n/a
	NM_130770
	n/a
	NP_570126
	n/a
	Wikidata
View/Edit Human

5-hydroxytryptamine receptor 3C is a protein that in humans is encoded by the HTR3C gene.^[3]^[4] The protein encoded by this gene is a subunit of the 5-HT3 receptor.^[4]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000178084 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene. 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.
^ ^a ^b Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ (May 2004). "The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance". Biochem Soc Trans. 32 (Pt3): 547–52. doi:10.1042/BST0320547. PMID 15157181.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000178084 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12801637-3] Niesler B, Frank B, Kapeller J, Rappold GA (Jun 2003). "Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E". Gene. 310: 101–11. doi:10.1016/S0378-1119(03)00503-1. PMID 12801637.

[pmid15157181-4] Peters JA, Kelley SP, Dunlop JI, Kirkness EF, Hales TG, Lambert JJ (May 2004). "The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance". Biochem Soc Trans. 32 (Pt3): 547–52. doi:10.1042/BST0320547. PMID 15157181.

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