| Haloacetate dehalogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Rhodopseudomonas palustris haloacetate dehalogenase | |||||||||
| Identifiers | |||||||||
| EC no. | 3.8.1.3 | ||||||||
| CAS no. | 37289-40-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a haloacetate dehalogenase (EC 3.8.1.3) is an enzyme that catalyzes the chemical reaction
- haloacetate + H2O glycolate + halide
Thus, the two substrates of this enzyme are haloacetate and H2O, whereas its two products are glycolate and halide. For examples, in the case of fluoroacetate in will produce glycolate and fluoride.
This enzyme belongs to the family of hydrolases, one of the largest known enzyme families comprising approximately 1% of the genes in the human genome, exists as a homodimer, and acts specifically on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is haloacetate halidohydrolase. This enzyme is also called monohaloacetate dehalogenase and fluoroacetate dehalogenase. This enzyme participates in gamma-hexachlorocyclohexane degradation and 1,2-dichloroethane degradation.