Haplogroup T-M184

This article is about the human Y-chromosome haplogroup T-M184. For the unrelated human mtDNA Haplogroup, see Haplogroup T (mtDNA).
Haplogroup T-M184
Possible time of origin26,000 BC BP[1]
Possible place of originWestern Asia.[2][3]
AncestorLT
DescendantsT1 (T-L206); T2 (T-PH110)
Defining mutationsM184/PAGES34/USP9Y+3178, M272, PAGES129, L810, L455, L452, L445
Highest frequenciesDir, Isaaq (Horn of Africa); Toubou (Chad); Antemoro (Madagascar);

Haplogroup T-M184, also known as Haplogroup T, is a human Y-chromosome DNA haplogroup. The unique-event polymorphism that defines this clade is the single-nucleotide polymorphism known as M184.[4]

Detailed representation of the presence of Haplogroup T in Europe and surrounding areas.

T-M184 is unusual in that it is both geographically widespread and relatively rare. T1 (T-L206) – the numerically dominant primary branch of T-M184 – appears to have originated in Western Asia, and spread from there into East Africa, South Asia, Europe, Egypt and adjoining regions. T1* may have expanded with the Pre-Pottery Neolithic B culture (PPNB) which originated in West Asia.

Subclades of T-M70 appear to have been present in Europe since the Neolithic with Neolithic Farmers from Western Asia. The moderately high frequency (~18%) of T1b* chromosomes in the Lemba of southern Africa supports the hypothesis of a West Asian origin for their paternal line.[5]

  1. ^ "T YTree". www.yfull.com.
  2. ^ Harney, Éadaoin; May, Hila; Shalem, Dina; Rohland, Nadin; Mallick, Swapan; Lazaridis, Iosif; Sarig, Rachel; Stewardson, Kristin; Nordenfelt, Susanne; Patterson, Nick; Hershkovitz, Israel; Reich, David (20 August 2018). "Ancient DNA from Chalcolithic Israel reveals the role of population mixture in cultural transformation". Nature Communications. 9 (1): 3336. Bibcode:2018NatCo...9.3336H. doi:10.1038/s41467-018-05649-9. PMC 6102297. PMID 30127404.
  3. ^ Elkamel, Sarra; Marques, Sofia L.; Alvarez, Luis; Gomes, Veronica; Boussetta, Sami; Mourali-Chebil, Soufia; Khodjet-El-Khil, Houssein; Cherni, Lotfi; Benammar-Elgaaied, Amel; Prata, Maria J. (3 August 2021). "Insights into the Middle Eastern paternal genetic pool in Tunisia: high prevalence of T-M70 haplogroup in an Arab population". Scientific Reports. 11 (1): 15728. Bibcode:2021NatSR..1115728E. doi:10.1038/s41598-021-95144-x. PMC 8333252. PMID 34344940.
  4. ^ Other SNPs – M272, PAGES129, L810, L455, L452, and L445 – are considered to be phylogenetically equivalent to M184.
  5. ^ Cite error: The named reference Mendez2011 was invoked but never defined (see the help page).