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The name Helderberg, meaning bright or clear mountain in Afrikaans and Dutch, may refer to:
- The Helderberg wine-producing region in the Western Cape, South Africa
- The Helderberg Mountain for which the above region is named
- The Boeing 747 named Helderberg on Flight SA 295 that crashed near Mauritius in 1987
- The container ship SA Helderberg
- The Helderberg Escarpment, at the northern end of the Catskill Mountains near Albany, New York, USA
- The Helderberg Formation, a geologic formation in Pennsylvania, Maryland and West Virginia, US
- The Helderberg Mountains, a mountain range in New York