Heran Darwin

Heran Darwin
Born
Santa Monica, California, United States
CitizenshipUnited States of America
Alma materUniversity of California, Los Angeles
Scientific career
FieldsMicrobiology
InstitutionsNew York University

Katerina Heran Darwin (née Hong) is an American microbiologist and professor of microbiology at New York University Grossman School of Medicine.[1] Her research interests include the bacterial proteasome[2] and the antimicrobial effects of host-produced effectors including nitric oxide,[3][4] copper,[5][6][7] and aldehydes[8]

  1. ^ "Heran Darwin". med.nyu.edu. Retrieved 2024-05-12.
  2. ^ Jastrab, Jordan B.; Wang, Tong; Murphy, J. Patrick; Bai, Lin; Hu, Kuan; Merkx, Remco; Huang, Jessica; Chatterjee, Champak; Ovaa, Huib; Gygi, Steven P.; Li, Huilin; Darwin, K. Heran (2015-03-23). "An adenosine triphosphate-independent proteasome activator contributes to the virulence of Mycobacterium tuberculosis". Proceedings of the National Academy of Sciences. 112 (14): E1763-72. Bibcode:2015PNAS..112E1763J. doi:10.1073/pnas.1423319112. ISSN 0027-8424. PMC 4394314. PMID 25831519.
  3. ^ Samanovic, Marie I.; Tu, Shengjiang; Novák, Ondřej; Iyer, Lakshminarayan M.; McAllister, Fiona E.; Aravind, L.; Gygi, Steven P.; Hubbard, Stevan R.; Strnad, Miroslav; Darwin, K. Heran (March 2015). "Proteasomal Control of Cytokinin Synthesis Protects Mycobacterium tuberculosis against Nitric Oxide". Molecular Cell. 57 (6): 984–994. doi:10.1016/j.molcel.2015.01.024. ISSN 1097-2765. PMC 4369403. PMID 25728768.
  4. ^ Darwin, K. Heran; Ehrt, Sabine; Gutierrez-Ramos, José-Carlos; Weich, Nadine; Nathan, Carl F. (2003-12-12). "The Proteasome of Mycobacterium tuberculosis Is Required for Resistance to Nitric Oxide". Science. 302 (5652): 1963–1966. Bibcode:2003Sci...302.1963D. doi:10.1126/science.1091176. ISSN 0036-8075. PMID 14671303.
  5. ^ Festa, Richard A.; Jones, Marcus B.; Butler-Wu, Susan; Sinsimer, Daniel; Gerads, Russell; Bishai, William R.; Peterson, Scott N.; Darwin, K. Heran (2010-10-29). "A novel copper-responsive regulon in Mycobacterium tuberculosis". Molecular Microbiology. 79 (1): 133–148. doi:10.1111/j.1365-2958.2010.07431.x. ISSN 0950-382X. PMC 3052634. PMID 21166899.
  6. ^ Limón, Gina; Samhadaneh, Nora M.; Pironti, Alejandro; Darwin, K. Heran (2022-10-02). "Aldehyde inactivation of the RicR regulon sensitizesMycobacterium tuberculosisto copper". doi:10.1101/2022.09.30.510424. Retrieved 2024-05-12. {{cite journal}}: Cite journal requires |journal= (help)
  7. ^ Shi, Xiaoshan; Festa, Richard A.; Ioerger, Thomas R.; Butler-Wu, Susan; Sacchettini, James C.; Darwin, K. Heran; Samanovic, Marie I. (2014-02-28). "The Copper-Responsive RicR Regulon Contributes to Mycobacterium tuberculosis Virulence". mBio. 5 (1). doi:10.1128/mbio.00876-13. ISSN 2161-2129. PMC 3944814. PMID 24549843.
  8. ^ Darwin, K. Heran; Stanley, Sarah A. (April 2022). "The aldehyde hypothesis: metabolic intermediates as antimicrobial effectors". Open Biology. 12 (4). doi:10.1098/rsob.220010. ISSN 2046-2441. PMC 9006002. PMID 35414258.