Hereditary gingival fibromatosis

Hereditary gingival fibromatosis
Other namesAutosomal dominant gingival hyperplasia, idiopathic gingival hyperplasia
SpecialtyDentistry

Hereditary gingival fibromatosis (HGF), also known as idiopathic gingival hyperplasia, is a rare condition of gingival overgrowth.[1] HGF is characterized as a benign, slowly progressive, nonhemorrhagic, fibrous enlargement of keratinized gingiva. It can cover teeth in various degrees, and can lead to aesthetic disfigurement.[2] Fibrous enlargement is most common in areas of maxillary and mandibular tissues of both arches in the mouth.[1] Phenotype and genotype frequency of HGF is 1:175,000 where males and females are equally affected but the cause is not entirely known.[2][3] It mainly exists as an isolated abnormality but can also be associated with a multi-system syndrome.[1]

  1. ^ a b c Poulami Majumder, Vineet Nair, Malancha Mukherjee, Sujoy Ghosh, and Subrata Kumar Dey, "The Autosomal Recessive Inheritance of Hereditary Gingival Fibromatosis", Case Reports in Dentistry, vol. 2013, Article ID 432864, 4 pages, 2013. doi:10.1155/2013/432864
  2. ^ a b Thomas C. Hart, Yingze Zhang, Michael C. Gorry, P. Suzanne Hart, Margaret Cooper, Mary L. Marazita, Jared M. Marks, Jose R. Cortelli, Debora Pallos Am J Hum Genet. 2002 April; 70(4): 943–954. Published online 2002 February 26.
  3. ^ K. B. Butchi, K. Pavankumar, B. R. Anuradha, and N. Arora, "Hereditary gingival fibromatosis—a case report and management using a novel surgical technique," Revista Sul-Brasileira de Odontologia, vol. 8, no. 4, pp. 453–458, 2011.