Hildegard Lamfrom

Hildegard Lamfrom
Born(1922-06-19)June 19, 1922
Augsburg, Germany
DiedAugust 28, 1984(1984-08-28) (aged 62)
La Jolla, California
Known forprotein translation
Scientific career
Fieldsbiochemistry, molecular biology
InstitutionsCedars of Lebanon Hospital, Carlsberg Laboratory, Caltech, MRC Laboratory, Institut de Biologie Physico-Chimique, Institute of Molecular Biology in Eugene, Oregon, UCSD, Harvard Medical School
Thesis (1949)
Doctoral advisorHarry Goldblatt

Hildegard Lamfrom was a German-American molecular biologist/biochemist. She helped develop one of the first in-vitro translation systems, using rabbit reticulocyte lysate to study protein synthesis (a process called translation) in a cell-free context.[1] This allowed her to make a number of contributions to the field including providing some of the first direct evidence for the existence of messenger RNA (mRNA) as a protein template, as well as the existence of polyribosomes (aka polysomes) (multiple ribosomes translating on the same mRNA).[2]

  1. ^ Cite error: The named reference :2 was invoked but never defined (see the help page).
  2. ^ "Hildegard Lamfrom '43". Reed Magazine | In Memoriam. Retrieved 2020-09-25.