Histoplasma duboisii

Histoplasma duboisii
Scientific classification Edit this classification
Domain: Eukaryota
Kingdom: Fungi
Division: Ascomycota
Class: Eurotiomycetes
Order: Onygenales
Family: Ajellomycetaceae
Genus: Histoplasma
Species:
H. duboisii
Binomial name
Histoplasma duboisii
Vanbreus. (1952)
Synonyms
  • Histoplasma capsulatum var. duboisii (Vanbreus.) Cif. (1960)

Histoplasma duboisii is a saprotrophic fungus responsible for the invasive infection known as African histoplasmosis.[1] This species is a close relative of Histoplasma capsulatum, the agent of classical histoplasmosis, and the two occur in similar habitats.[1] Histoplasma duboisii is restricted to continental Africa and Madagascar, although scattered reports have arisen from other places usually in individuals with an African travel history.[2] Like, H. capsulatum, H. duboisii is dimorphic – growing as a filamentous fungus at ambient temperature and a yeast at body temperature.[2] It differs morphologically from H. capsulatum by the typical production of a large-celled yeast form.[2] Both agents cause similar forms of disease, although H. duboisii predominantly causes cutaneous and subcutaneous disease in humans and non-human primates.[2][3] The agent responds to many antifungal drug therapies used to treat serious fungal diseases.[3]

  1. ^ a b Cite error: The named reference Loulergue was invoked but never defined (see the help page).
  2. ^ a b c d Cite error: The named reference Rippon1988 was invoked but never defined (see the help page).
  3. ^ a b Cite error: The named reference Gugani 2000 was invoked but never defined (see the help page).