Hyaluronoglucuronidase

Hyaluronoglucuronidase
Identifiers
EC no.3.2.1.36
CAS no.37288-34-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Hyaluronoglucuronidase (EC 3.2.1.36, hyaluronidase, glucuronoglucosaminoglycan hyaluronate lyase, orgelase) is an enzyme with systematic name hyaluronate 3-glycanohydrolase.[1][2] This enzyme catalyses the following chemical reaction

Random hydrolysis of (1→3)-linkages between β-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate
  1. ^ Linker A, Meyer K, Hoffman P (April 1960). "The production of hyaluronate oligosaccharides by leech hyaluronidase and alkali". The Journal of Biological Chemistry. 235: 924–7. PMID 14417285.
  2. ^ Meyer K, Hoffman P, Linker A (1960). "Hyaluronidases". In Boyer PD, Lardy H, Myrbaumlck K (eds.). The Enzymes. Vol. 4 (2nd ed.). New York: Academic Press. pp. 447–460.