 | It has been suggested that this article should be split into articles titled Hypervariable region (nucleic acid) and Hypervariable region (antibody). (discuss) (June 2022) |
A hypervariable region (HVR) is a location within nuclear DNA or the D-loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case of nuclear DNA) or have substitutions (in the case of mitochondrial DNA). Changes or repeats in the hypervariable region are highly polymorphic.