Names | |
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IUPAC name
3-[(1R-2-Methylidenecyclopropyl]-L-alanine
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Systematic IUPAC name
(2S)-2-Amino-3-[(1R)-2-methylidenecyclopropyl]propanoic acid | |
Other names
Hypoglycin A; Hypoglycine; 2-Methylenecyclopropanylalanine
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Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.189.936 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C7H11NO2 | |
Molar mass | 141.170 g·mol−1 |
Melting point | 282 °C (540 °F; 555 K) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Hypoglycin A is a naturally occurring amino acid derivative found in the unripened fruit of the Ackee tree (Blighia sapida)[1] and in the seeds of the box elder tree (Acer negundo).[2] It is toxic if ingested, and is the causative agent of Jamaican vomiting sickness.[1] A 2017 Lancet report established a link between the consumption of unripened lychees (containing hypoglycin A or methylenecyclopropylglycine (MCPG)) resulting in hypoglycaemia and death from acute toxic encephalopathy.[3]