INSL3

INSL3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2H8B, 2K6T, 2K6U
Identifiers
Aliases	INSL3, RLF, RLNL, ley-I-L, insulin like 3
External IDs	OMIM: 146738; MGI: 108427; HomoloGene: 4048; GeneCards: INSL3; OMA:INSL3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	17,821,574 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	72,143,219 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; testicle; ; gonad; ; granulocyte; ; buccal mucosa cell; ; blood; ; spleen; ; appendix; ; right ovary;
	Top expressed in
	testicle; ; spermatocyte; ; spleen; ; islet of Langerhans; ; bone marrow; ; urinary bladder; ; adrenal gland; ; duodenum; ; thymus; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protease binding; signaling receptor binding; insulin receptor binding; hormone activity; G protein-coupled receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	cell-cell signaling; positive regulation of wound healing; positive regulation of epithelial cell migration; spermatogenesis; regulation of signaling receptor activity; G protein-coupled receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3640
	16336
	ENSG00000248099
	ENSMUSG00000079019
	P51460
	O09107; Q5RL10
	NM_005543; NM_001265587
	NM_013564
	NP_001252516; NP_005534
	NP_038592
	Wikidata
View/Edit Human	View/Edit Mouse

Insulin-like 3 is a protein that in humans is encoded by the INSL3 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000248099 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000079019 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Burkhardt E, Adham IM, Brosig B, Gastmann A, Mattei MG, Engel W (March 1994). "Structural organization of the porcine and human genes coding for a Leydig cell-specific insulin-like peptide (LEY I-L) and chromosomal localization of the human gene (INSL3)". Genomics. 20 (1): 13–9. doi:10.1006/geno.1994.1121. PMID 8020942.
^ "Entrez Gene: INSL3 insulin-like 3 (Leydig cell)".