ImKTX58

ImKTX58
Identifiers
3D model (JSmol)
  • InChI=1S/C183H283N57O52S8/c1-15-91(8)143(236-159(269)111(34-21-25-57-187)215-178(288)145(94(11)244)237-163(273)121(68-101-73-197-87-206-101)223-174(284)141(89(4)5)234-148(258)105(188)46-49-133(189)248)177(287)216-115(53-62-294-14)158(268)229-128-81-297-299-83-130(169(279)220-118(64-97-40-44-103(247)45-41-97)161(271)224-123(181(291)292)65-98-70-200-106-30-17-16-29-104(98)106)232-179(289)146(95(12)245)238-171(281)131-84-300-298-82-129-168(278)221-120(67-100-72-196-86-205-100)150(260)202-76-137(252)233-140(88(2)3)176(286)239-144(93(10)243)173(283)203-75-136(251)209-108(35-26-58-198-182(191)192)151(261)207-92(9)147(257)218-119(66-99-71-195-85-204-99)149(259)201-74-135(250)208-107(31-18-22-54-184)152(262)227-126(166(276)214-114(52-61-293-13)157(267)222-122(69-134(190)249)162(272)211-109(32-19-23-55-185)153(263)210-110(155(265)230-131)33-20-24-56-186)79-295-296-80-127(167(277)219-117(63-96-38-42-102(246)43-39-96)160(270)217-116(48-51-139(255)256)180(290)240-60-28-37-132(240)172(282)231-129)228-156(266)113(47-50-138(253)254)213-154(264)112(36-27-59-199-183(193)194)212-164(274)124(77-241)226-175(285)142(90(6)7)235-165(275)125(78-242)225-170(128)280/h16-17,29-30,38-45,70-73,85-95,105,107-132,140-146,200,241-247H,15,18-28,31-37,46-69,74-84,184-188H2,1-14H3,(H2,189,248)(H2,190,249)(H,195,204)(H,196,205)(H,197,206)(H,201,259)(H,202,260)(H,203,283)(H,207,261)(H,208,250)(H,209,251)(H,210,263)(H,211,272)(H,212,274)(H,213,264)(H,214,276)(H,215,288)(H,216,287)(H,217,270)(H,218,257)(H,219,277)(H,220,279)(H,221,278)(H,222,267)(H,223,284)(H,224,271)(H,225,280)(H,226,285)(H,227,262)(H,228,266)(H,229,268)(H,230,265)(H,231,282)(H,232,289)(H,233,252)(H,234,258)(H,235,275)(H,236,269)(H,237,273)(H,238,281)(H,239,286)(H,253,254)(H,255,256)(H,291,292)(H4,191,192,198)(H4,193,194,199)/t91-,92-,93+,94+,95+,105-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,140-,141-,142-,143-,144-,145-,146-/m0/s1
    Key: YZPIASKHVZBKSO-ABEJSSCSSA-N
  • N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CS3)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CS4)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CS5)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)NCC(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC1=CN=C-N1)C(=O)NCC(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS4)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CS5)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CS3)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CC(=CN2)C1=C2C=CC=C1)C(=O)O
Properties
C183H283N57O52S8
Molar mass 4370.10 g·mol−1
Related compounds
Related compounds
 LmKTX10, ImKTx88
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

ImKTX58 (also known as kappa-Buthitoxin-Im1a) is a peptide toxin from the venom of the scorpion species Isometrus maculatus (also known as the lesser brown scorpion). It is known for its selective inhibition of Kv1.3 channels, on which it acts as a pore-blocker.